Tcg Crossover Management, Llc
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$3.50B
Q ending 2026-03-31
Prior quarter
$3.02B
Q ending 2025-12-31
Change
+15.7% QoQ · +376.8% YoY
Positions
49
reported holdings
Largest positions
All 49 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Abivax Sa American Depositary Shar | ABVX | Shares | $721.7M | 6.5M |
| Cg Oncology Inc | CGON | Shares | $248.4M | 3.7M |
| Tango Therapeutics Inc | TNGX | Shares | $220.3M | 10.5M |
| Cogent Biosciences Inc | COGT | Shares | $190.4M | 4.9M |
| Centessa Pharmaceuticals Plc | 260 | Shares | $170.3M | 4.3M |
| Dianthus Therapeutics Inc | DNTH | Shares | $140.7M | 1.7M |
| Tyra Biosciences Inc | TYRA | Shares | $124.4M | 3.2M |
| Immunovant Inc | IMVT | Shares | $110.7M | 4.5M |
| Biocryst Pharmaceuticals Inc | BCRX | Shares | $104.9M | 11.0M |
| Mirum Pharmaceuticals Inc | MIRM | Shares | $98.1M | 1.1M |
| Vor Biopharma Inc | VOR | Shares | $96.5M | 5.7M |
| Spyre Therapeutics Inc | SYRE | Shares | $95.9M | 1.9M |
| Amylyx Pharmaceuticals Inc | AMLX | Shares | $86.8M | 6.2M |
| Disc Medicine Inc | IRON | Shares | $85.8M | 1.3M |
| Dyne Therapeutics Inc | DYN | Shares | $83.7M | 4.6M |
| Monte Rosa Therapeutics Inc | GLUE | Shares | $76.0M | 4.6M |
| Savara Inc | SVRA | Shares | $67.5M | 12.4M |
| Revolution Medicines Inc | RVMD | Shares | $56.1M | 576K |
| Kodiak Sciences Inc | KOD | Shares | $55.1M | 1.4M |
| Lb Pharmaceuticals Inc | LBRX | Shares | $45.3M | 1.8M |
| Surrozen Inc | SRZN | Shares | $42.9M | 1.5M |
| Adc Therapeutics Sa | Shares | $42.7M | 11.4M | |
| Relay Therapeutics Inc | RLAY | Shares | $42.5M | 4.3M |
| Fulcrum Therapeutics Inc | FULC | Shares | $40.3M | 5.3M |
| Biohaven Ltd | Shares | $39.2M | 4.6M | |
| Century Therapeutics Inc | IPSC | Shares | $39.0M | 17.8M |
| Tectonic Therapeutic Inc | TECX | Shares | $37.2M | 1.2M |
| Perspective Therapeutics Inc | CATX | Shares | $33.0M | 7.9M |
| Xencor Inc | XNCR | Shares | $29.6M | 2.5M |
| Entrada Therapeutics Inc | TRDA | Shares | $28.9M | 2.3M |
| Alx Oncology Holdings Inc | ALXO | Shares | $26.1M | 13.0M |
| Arvinas Holding Co Llc | ARVN | Shares | $25.3M | 2.4M |
| Janux Therapeutics Inc | JANX | Shares | $24.9M | 1.8M |
| Agomab Therapeutics Nv | AGMB | Shares | $21.5M | 2.1M |
| Alector Inc | ALEC | Shares | $21.5M | 10.0M |
| Mbx Biosciences Inc | MBX | Shares | $19.4M | 650K |
| Silence Therapeutics Plc | SLN | Shares | $16.0M | 3.0M |
| Liquidia Technologies Inc | LQDA | Shares | $15.2M | 403K |
| Ocular Therapeutix Inc | OCUL | Shares | $14.0M | 1.6M |
| Avalo Therapeutics Inc | AVTX | Shares | $11.0M | 738K |
| Urogen Pharma Ltd | Shares | $7.3M | 405K | |
| Monopar Therapeutics Inc | MNPR | Shares | $7.2M | 132K |
| Context Therapeutics Inc | CNTX | Shares | $7.0M | 2.7M |
| Structure Therapeutics Inc | GPCR | Shares | $6.8M | 140K |
| Cullinan Therapeutics Inc | CGEM | Shares | $5.8M | 407K |
| Korro Bio Inc | KRRO | Shares | $4.7M | 416K |
| Leonabio Inc | LONA | Shares | $4.7M | 464K |
| Upstream Bio Inc | UPB | Shares | $1.6M | 181K |
| Vistagen Therapeutics Inc | VTGN | Shares | $1.5M | 2.7M |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.