Sio Capital Management, Llc

Institutional manager — quarterly 13F holdings, Q ending 2026-03-31

Reported value
$697.3M
Q ending 2026-03-31
Prior quarter
$635.7M
Q ending 2025-12-31
Change
+9.7% QoQ · +107.7% YoY
Positions
76
reported holdings

Largest positions

All 76 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
HoldingTickerTypeValueShares
Maximus IncMMSShares$49.3M769K
Waystar Hldg CorpWAYShares$39.6M1.6M
Icon PlcShares$33.9M306K
Cencora IncCORShares$31.7M101K
Dianthus Therapeutics IncDNTHShares$31.1M370K
Anteris Technologies GlobalAVRShares$29.9M5.4M
Corcept Therapeutics IncCORTShares$27.2M675K
Livanova PlcShares$26.8M422K
Tyra Biosciences IncTYRAShares$23.2M605K
Celcuity IncCELCShares$22.1M194K
Gsk PlcGSKShares$21.3M386K
Ani Pharmaceuticals IncANIPShares$20.4M266K
Abbott LaboratoriesABTShares$19.2M187K
Embecta CorpEMBCShares$16.3M1.8M
Abivax SaABVXShares$15.1M136K
Vir Biotechnology IncVIRShares$13.4M1.5M
Haemonetics Corp MassHAEShares$12.4M221K
Sionna Therapeutics IncSIONShares$11.8M294K
Sanofi SaSNYShares$11.5M240K
Rapport Therapeutics IncRAPPShares$11.5M367K
Teleflex IncorporatedTFXShares$11.3M95K
Biomarin Pharmaceutical IncBMRNShares$11.0M194K
Cross Ctry Healthcare IncCCRNShares$10.3M1.1M
Protara Therapeutics IncTARAShares$10.3M2.0M
Structure Therapeutics IncGPCRShares$10.1M209K
Biohaven LtdShares$9.8M1.2M
Monopar Therapeutics IncMNPRShares$9.5M174K
Eyepoint IncEYPTShares$9.3M722K
Crinetics Pharmaceuticals InCRNXShares$9.1M250K
Edgewise Therapeutics IncEWTXShares$8.5M269K
Compass Pathways PlcCMPSShares$8.3M1.5M
Ocular Therapeutix IncOCULShares$8.2M969K
Aquestive Therapeutics IncAQSTShares$8.0M1.9M
Relmada Therapeutics IncRLMDShares$6.7M965K
Oruka Therapeutics IncORKAShares$6.5M132K
Zenas Biopharma IncZBIOShares$6.5M332K
Bright Minds Biosciences IncDRUGShares$6.3M86K
Quidelortho CorpQDELShares$5.9M359K
Zimmer Biomet Holdings IncZBHShares$5.7M63K
Replimune Group IncREPLShares$5.5M720K
Organon & CoOGNShares$5.2M866K
Onkure Therapeutics IncOKURShares$4.5M1.1M
Disc Medicine IncIRONShares$4.2M65K
Pmv Pharmaceuticals IncPMVPShares$3.8M3.1M
Immunome IncIMNMShares$3.6M165K
Integra Lifesciences Hldgs CIARTShares$3.6M383K
Savara IncSVRAShares$3.4M614K
Centene Corp DelCNCPut$3.3M100K
Proqr Therapeutics N VShares$3.2M2.0M
Shoulder Innovations IncSIShares$3.1M211K
Ovid Therapeutics IncOVIDShares$2.8M1.3M
Kymera Therapeutics IncKYMRShares$2.7M32K
Aligos Therapeutics IncALGSShares$2.4M327K
Context Therapeutics IncCNTXShares$2.4M918K
An2 Therapeutics IncANTXShares$2.2M657K
Serina Therapeutics IncSERShares$1.9M1.0M
Ibio IncIBIOShares$1.7M904K
Adagio Med Hldgs IncADGMShares$1.5M1.3M
Xilio Therapeutics IncXLOShares$1.3M152K
Bridgebio Oncology TherapeutBBOTShares$1.2M131K
Hyperfine IncHYPRShares$1.1M1.0M
Senseonics Hldgs IncSENSShares$771K116K
Foghorn Therapeutics IncFHTXShares$587K123K
Terns Pharmaceuticals Inc430Shares$532K10K
Enanta Pharmaceuticals IncENTAShares$505K40K
Tela Bio IncTELAShares$395K636K
Neuroone Med Technologies CoShares$386K497K
Boundless Bio IncBOLDShares$180K164K
Nyxoah S AShares$148K51K
Modular Med IncMODDShares$138K26K
Elicio Therapeutics IncELTXPut$125K12K
Erasca IncERASShares$81K5K
Oscar Health IncOSCRPut$34K3K
Rocket Pharmaceuticals IncRCKTWShares$7K400K
Humacyte IncHUMAWShares$5K50K
Simulations Plus IncSLPShares$2K200

Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.