Silverarc Capital Management, Llc
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$979.8M
Q ending 2026-03-31
Prior quarter
$720.1M
Q ending 2025-12-31
Change
+36.1% QoQ · +100.4% YoY
Positions
73
reported holdings
Largest positions
All 73 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Spdr Series Trust | Put | $105.4M | 825K | |
| Kalvista Pharmaceuticals Inc | 4XC1 | Shares | $57.9M | 2.9M |
| Dianthus Therapeutics Inc | DNTH | Shares | $54.9M | 655K |
| Cogent Biosciences Inc | COGT | Shares | $50.6M | 1.3M |
| Celcuity Inc | CELC | Shares | $40.9M | 358K |
| Immunome Inc | IMNM | Shares | $40.5M | 1.9M |
| Kodiak Sciences Inc | KOD | Shares | $37.8M | 992K |
| Nuvalent Inc | 5AX | Shares | $36.4M | 355K |
| Abivax Sa | ABVX | Shares | $33.7M | 303K |
| Monte Rosa Therapeutics Inc | GLUE | Shares | $32.9M | 2.0M |
| Erasca Inc | ERAS | Shares | $30.0M | 1.9M |
| Ascendis Pharma A/S | Shares | $28.5M | 125K | |
| Urogen Pharma Ltd | Shares | $27.0M | 1.5M | |
| Rhythm Pharmaceuticals Inc | RYTM | Shares | $26.6M | 306K |
| Praxis Precision Medicines I | PRAX | Shares | $23.1M | 72K |
| Zenas Biopharma Inc | ZBIO | Shares | $22.2M | 1.1M |
| Syndax Pharmaceuticals Inc | SNDX | Shares | $20.8M | 889K |
| Centessa Pharmaceuticals Plc | 260 | Shares | $18.5M | 466K |
| Scholar Rock Hldg Corp | SRRK | Shares | $16.7M | 340K |
| Alkermes Plc | Shares | $16.3M | 460K | |
| Oric Pharmaceuticals Inc | ORIC | Shares | $13.9M | 1.1M |
| Disc Medicine Inc | IRON | Shares | $12.5M | 196K |
| Helix Acquisition Corp Iii | Shares | $12.3M | 1.2M | |
| Xenon Pharmaceuticals Inc | XENE | Shares | $11.5M | 198K |
| Cg Oncology Inc | CGON | Shares | $11.3M | 166K |
| Immunovant Inc | IMVT | Shares | $10.3M | 414K |
| Spyre Therapeutics Inc | SYRE | Shares | $9.4M | 187K |
| Biogen Inc | BIIB | Shares | $9.3M | 51K |
| Guardant Health Inc | GH | Shares | $9.1M | 99K |
| Vaxcyte Inc | PCVX | Shares | $8.4M | 145K |
| Uniqure Nv | Call | $8.2M | 500K | |
| Savara Inc | SVRA | Shares | $7.8M | 1.4M |
| Benitec Biopharma Inc | BNTC | Shares | $7.6M | 718K |
| Syndax Pharmaceuticals Inc | Call | $7.5M | 320K | |
| Oruka Therapeutics Inc | ORKA | Shares | $7.4M | 151K |
| Compugen Ltd | Shares | $7.1M | 3.3M | |
| Celcuity Inc | Call | $6.2M | 55K | |
| Trevi Therapeutics Inc | TRVI | Shares | $6.1M | 511K |
| Insmed Inc | INSM | Shares | $5.9M | 36K |
| Veracyte Inc | VCYT | Shares | $5.8M | 180K |
| Cerus Corp | CERS | Shares | $5.8M | 3.2M |
| Celldex Therapeutics Inc New | CLDX | Shares | $5.7M | 178K |
| C4 Therapeutics Inc | CCCC | Shares | $5.0M | 1.9M |
| Cytokinetics Inc | CYTK | Shares | $4.7M | 71K |
| Climb Bio Inc | CLYM | Shares | $4.7M | 685K |
| Compass Therapeutics Inc | CMPX | Shares | $4.5M | 859K |
| Surrozen Inc | SRZN | Shares | $4.2M | 144K |
| Contineum Therapeutics Inc | CTNM | Shares | $3.9M | 302K |
| Zura Bio Ltd | Shares | $3.3M | 561K | |
| Fulcrum Therapeutics Inc | FULC | Shares | $3.2M | 420K |
| Fulcrum Therapeutics Inc | Call | $3.0M | 392K | |
| Abeona Therapeutics Inc | ABEO | Shares | $2.9M | 649K |
| Camp4 Therapeutics Corp | CAMP | Shares | $2.9M | 654K |
| Annexon Inc | ANNX | Shares | $2.8M | 496K |
| Elutia Inc | ELUT | Shares | $2.6M | 2.5M |
| Crescent Biopharma Inc. | Shares | $2.4M | 131K | |
| Monopar Therapeutics Inc | MNPR | Shares | $2.4M | 43K |
| Ovid Therapeutics Inc | OVID | Shares | $2.2M | 1.0M |
| Nextcure Inc | NXTC | Shares | $1.9M | 176K |
| Compass Pathways Plc | CMPS | Shares | $1.7M | 300K |
| Neumora Therapeutics Inc. | NMRA | Shares | $1.6M | 818K |
| Sionna Therapeutics Inc | SION | Shares | $1.6M | 39K |
| Tela Bio Inc | TELA | Shares | $1.4M | 2.3M |
| Edgewise Therapeutics Inc | EWTX | Shares | $1.3M | 43K |
| Replimune Group Inc | REPL | Shares | $1.3M | 172K |
| Generate Biomedicines Inc | GENB | Shares | $1.3M | 100K |
| Compass Therapeutics Inc | Call | $912K | 172K | |
| Radiopharm Theranostics Ltd | RADX | Shares | $806K | 187K |
| Fractyl Health Inc | GUTS | Shares | $779K | 1.7M |
| Ibio Inc | IBIO | Shares | $429K | 226K |
| Adagio Med Hldgs Inc | ADGM | Shares | $290K | 252K |
| Aardvark Therapeutics Inc | AARD | Shares | $127K | 34K |
| Rocket Pharmaceuticals Inc | RCKTW | Shares | $2K | 105K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.