Ra Capital Management, L.P.
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$9.44B
Q ending 2026-03-31
Prior quarter
$9.76B
Q ending 2025-12-31
Change
-3.3% QoQ · +57.6% YoY
Positions
85
reported holdings
Largest positions
All 85 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Ascendis Pharma A/S - Adr | Shares | $2.35B | 10.3M | |
| Vaxcyte Inc | PCVX | Shares | $666.8M | 11.5M |
| Rhythm Pharmaceuticals Inc | RYTM | Shares | $579.8M | 6.7M |
| Tyra Biosciences Inc | TYRA | Shares | $467.2M | 12.2M |
| Sionna Therapeutics Inc | SION | Shares | $397.1M | 9.9M |
| Edgewise Therapeutics Inc | EWTX | Shares | $328.5M | 10.4M |
| Newamsterdam Pharma Co Nv | Shares | $305.7M | 9.6M | |
| Nuvalent Inc-A | 5AX | Shares | $259.6M | 2.5M |
| Dianthus Therapeutics Inc | DNTH | Shares | $219.2M | 2.6M |
| Mineralys Therapeutics Inc | MLYS | Shares | $208.4M | 7.7M |
| Spyglass Pharma Inc | SGP | Shares | $207.8M | 8.0M |
| Wave Life Sciences Ltd | Shares | $195.6M | 27.0M | |
| Septerna Inc | SEPN | Shares | $168.1M | 7.0M |
| Disc Medicine Inc | IRON | Shares | $156.7M | 2.5M |
| Janux Therapeutics Inc | JANX | Shares | $155.5M | 11.2M |
| Biocryst Pharmaceuticals Inc | BCRX | Shares | $150.7M | 15.8M |
| Bicara Therapeutics Inc | BCAX | Shares | $144.3M | 7.3M |
| Praxis Precision Medicines I | PRAX | Shares | $120.4M | 374K |
| Gh Research Plc | Shares | $107.9M | 7.7M | |
| Zai Lab Ltd-Adr | ZLAB | Shares | $107.4M | 5.7M |
| Taysha Gene Therapies Inc | TSHA | Shares | $105.3M | 23.6M |
| Vor Biopharma Inc | VOR | Shares | $96.4M | 5.4M |
| Geron Corp | GERN | Shares | $95.0M | 63.8M |
| Ars Pharmaceuticals Inc | SPRY | Shares | $87.2M | 10.9M |
| Sarepta Therapeutics Inc | SRPT | Shares | $84.9M | 3.9M |
| Spyre Therapeutics Inc | SYRE | Shares | $81.8M | 1.6M |
| Evommune Inc | EVMN | Shares | $80.3M | 3.5M |
| Climb Bio Inc | CLYM | Shares | $77.4M | 11.3M |
| Solid Biosciences Inc | SLDB | Shares | $67.2M | 9.3M |
| Artiva Biotherapeutics Inc | ARTV | Shares | $63.5M | 9.9M |
| Damora Therapeutics Inc | DMRA | Shares | $62.1M | 2.4M |
| Xencor Inc | XNCR | Shares | $59.1M | 4.9M |
| Lb Pharmaceuticals Inc | LBRX | Shares | $54.5M | 2.2M |
| Jade Biosciences Inc | JBIO | Shares | $51.6M | 3.7M |
| Acumen Pharmaceuticals Inc | ABOS | Shares | $49.5M | 21.0M |
| 4D Molecular Therapeutics In | FDMT | Shares | $47.0M | 5.0M |
| Fulcrum Therapeutics Inc | FULC | Shares | $46.4M | 6.1M |
| Capricor Therapeutics Inc | CAPR | Shares | $45.8M | 1.5M |
| Century Therapeutics Inc | IPSC | Shares | $40.1M | 17.8M |
| Olema Pharmaceuticals Inc | OLMA | Shares | $38.8M | 2.6M |
| Lenz Therapeutics Inc | LENZ | Shares | $38.2M | 4.2M |
| Monopar Therapeutics Inc | MNPR | Shares | $36.6M | 667K |
| Pepgen Inc | PEPG | Shares | $35.5M | 20.1M |
| Design Therapeutics Inc | DSGN | Shares | $31.6M | 3.0M |
| Mirum Pharmaceuticals Inc | MIRM | Shares | $29.4M | 319K |
| Bioage Labs Inc | BIOA | Shares | $28.9M | 1.7M |
| Lexeo Therapeutics Inc | LXEO | Shares | $28.7M | 5.0M |
| Assembly Biosciences Inc | ASMB | Shares | $28.3M | 1.0M |
| Rezolute Inc | RZLT | Shares | $28.0M | 9.2M |
| Aktis Oncology Inc | AKTS | Shares | $26.9M | 1.5M |
| Alx Oncology Holdings Inc | ALXO | Shares | $26.1M | 13.0M |
| Aclaris Therapeutics Inc | ACRS | Shares | $25.5M | 6.8M |
| Ovid Therapeutics Inc | OVID | Shares | $23.8M | 10.7M |
| Nkarta Inc | NKTX | Shares | $22.8M | 10.8M |
| Travere Therapeutics Inc | TVTX | Shares | $22.2M | 747K |
| Grail Inc | GRAL | Shares | $22.1M | 428K |
| C4 Therapeutics Inc | CCCC | Shares | $21.0M | 8.0M |
| Relmada Therapeutics Inc | RLMD | Shares | $20.5M | 2.9M |
| Benitec Biopharma Inc | BNTC | Shares | $19.7M | 1.9M |
| Bright Minds Biosciences Inc | DRUG | Shares | $19.3M | 265K |
| Sutro Biopharma Inc | STRO | Shares | $17.8M | 715K |
| Contineum Therapeutics Inc-A | CTNM | Shares | $16.9M | 1.3M |
| Sab Biotherapeutics Inc | SABS | Shares | $16.9M | 4.4M |
| Inspire Medical Systems Inc | INSP | Shares | $16.8M | 326K |
| Anteris Technologies Global | AVR | Shares | $16.6M | 3.0M |
| Onkure Therapeutics Inc-A | OKUR | Shares | $16.6M | 4.0M |
| Hinge Health Inc-A | HNGE | Shares | $14.1M | 365K |
| Genedx Holdings Corp | WGS | Shares | $13.5M | 210K |
| Waystar Holding Corp | WAY | Shares | $12.8M | 529K |
| Helix Acquisition Corp-Cl A | Shares | $12.7M | 1.3M | |
| Palisade Bio Inc | PALI | Shares | $12.5M | 7.1M |
| Acrivon Therapeutics Inc | ACRV | Shares | $11.6M | 8.3M |
| Atrium Therapeutics Inc | RNA | Shares | $11.6M | 864K |
| Karyopharm Therapeutics Inc | KPTI | Shares | $10.7M | 1.9M |
| Avalo Therapeutics Inc | AVTX | Shares | $9.9M | 663K |
| Perceptive Capital Solutions | Shares | $8.2M | 750K | |
| Adicet Bio Inc | ACET | Shares | $8.1M | 1.2M |
| Newamsterdam Pharma Co Nv-27 | Shares | $6.7M | 333K | |
| Corvus Pharmaceuticals Inc | CRVS | Shares | $6.6M | 450K |
| Rani Therapeutics Holdings-A | RANI | Shares | $6.2M | 8.5M |
| Equillium Inc | EQ | Shares | $6.2M | 3.1M |
| Werewolf Therapeutics Inc | HOWL | Shares | $5.6M | 6.7M |
| Macrogenics Inc | MGNX | Shares | $5.4M | 1.9M |
| Maplight Therapeutics Inc | MPLT | Shares | $5.0M | 248K |
| Palatin Technologies Inc | PTN | Shares | $1.2M | 70K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.