Ishara Investments Lp
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$105.6M
Q ending 2026-03-31
Prior quarter
$87.5M
Q ending 2025-12-31
Change
+20.8% QoQ
Positions
37
reported holdings
Largest positions
All 37 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Praxis Precision Medicines I | PRAX | Shares | $7.3M | 23K |
| Axsome Therapeutics Inc. | AXSM | Shares | $6.9M | 41K |
| Praxis Precision Medicines I | PRAX | Put | $6.6M | 21K |
| Xeris Biopharma Holdings Inc | XERS | Shares | $5.9M | 1.0M |
| Kalvista Pharmaceuticals Inc | 4XC1 | Shares | $5.6M | 277K |
| Amicus Therapeutic | AM6 | Shares | $5.3M | 369K |
| Biomarin Pharmaceutical Inc | BMRN | Shares | $4.6M | 82K |
| Verastem Inc | VSTM | Shares | $4.3M | 820K |
| Ultragenyx Pharmaceutical In | RARE | Shares | $3.7M | 174K |
| Arrowhead Pharmaceuticals In | ARWR | Shares | $3.5M | 55K |
| Vaxcyte Inc | PCVX | Shares | $3.3M | 57K |
| Vera Therapeutics Inc | VERA | Shares | $3.3M | 82K |
| Travere Therapeutics Inc | TVTX | Shares | $3.3M | 111K |
| Moonlake Immunotherapeutics | MLTX | Shares | $3.2M | 174K |
| Zentalis Pharmaceuticals Inc | ZNTL | Shares | $2.9M | 1.2M |
| Scholar Rock Hldg Corp | SRRK | Shares | $2.8M | 57K |
| Acadia Pharmaceuticals Inc | ACAD | Shares | $2.7M | 123K |
| Ardelyx Inc | ARDX | Shares | $2.7M | 451K |
| Mineralys Therapeutics Inc | MLYS | Shares | $2.2M | 82K |
| Genmab A/S | GMAB | Shares | $2.2M | 82K |
| Dbv Technologies S A | DBVT | Shares | $2.1M | 103K |
| Catalyst Pharmaceuticals Inc | Shares | $2.0M | 82K | |
| Sionna Therapeutics Inc | SION | Shares | $2.0M | 49K |
| Contineum Therapeutics Inc | CTNM | Shares | $1.9M | 142K |
| Alnylam Pharmaceuticals Inc | ALNY | Shares | $1.7M | 5K |
| Ligand Pharmaceuticals Inc | LGND | Shares | $1.6M | 8K |
| Edgewise Therapeutics Inc | EWTX | Shares | $1.5M | 49K |
| Immatics N.V | Shares | $1.5M | 154K | |
| Lexicon Pharmaceuticals Inc | LXRX | Shares | $1.4M | 902K |
| Beam Therapeutics Inc | BEAM | Shares | $1.4M | 57K |
| Oric Pharmaceuticals Inc | ORIC | Shares | $1.3M | 103K |
| Newamsterdam Pharma Company | Shares | $1.2M | 37K | |
| Annexon Inc | ANNX | Shares | $965K | 174K |
| Ideaya Biosciences Inc | IDYA | Shares | $820K | 25K |
| Silence Therapeutics Plc | SLN | Shares | $740K | 141K |
| Ptc Therapeutics Inc | PTCT | Shares | $698K | 10K |
| Gossamer Bio Inc | GOSS | Shares | $269K | 820K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.