Ikarian Capital, Llc

Institutional manager — quarterly 13F holdings, Q ending 2026-03-31

Reported value
$1.23B
Q ending 2026-03-31
Prior quarter
$1.28B
Q ending 2025-12-31
Change
-3.8% QoQ · +51.8% YoY
Positions
161
reported holdings

Largest positions

Top 100 of 161 reported positions by value, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
HoldingTickerTypeValueShares
Spdr Series TrustXBIPut$102.2M800K
Terns Pharmaceuticals Inc430Shares$76.8M1.5M
Terns Pharmaceuticals Inc430Put$63.3M1.2M
Invesco Qqq TrQQQPut$57.7M100K
Ishares TrIWMPut$49.6M200K
Kodiak Sciences IncKODShares$48.3M1.3M
Cytokinetics IncCYTKPut$36.3M551K
Abivax SaABVXCall$32.7M293K
Bristol-Myers Squibb CoBMYPut$30.3M500K
Cytokinetics IncCYTKCall$26.9M408K
Alumis IncALMSShares$26.7M1.2M
Vaxcyte IncPCVXShares$24.9M429K
Praxis Precision Medicines IPRAXShares$23.1M72K
Harrow IncHROWShares$19.1M543K
Relmada Therapeutics IncRLMDShares$18.7M2.7M
Cytokinetics IncCYTKShares$18.7M284K
Tenax Therapeutics IncTENXShares$16.3M1.0M
Capricor Therapeutics IncCAPRShares$16.1M528K
Revolution Medicines IncRVMDShares$15.9M163K
Novo-Nordisk A SNVOCall$14.7M400K
Celldex Therapeutics Inc NewCLDXShares$14.6M461K
Pharvaris N VShares$13.8M487K
Connect Biopharma Hldgs LtdShares$13.1M5.4M
Bright Minds Biosciences IncDRUGShares$12.2M167K
Bridgebio Pharma IncBBIOShares$11.9M160K
Oruka Therapeutics IncORKAShares$11.9M242K
Alto Neuroscience IncANROShares$11.6M515K
Ani Pharmaceuticals IncANIPCall$11.5M150K
Soleno Therapeutics IncSLNOEURShares$11.5M344K
Maze Therapeutics IncMAZEShares$11.3M379K
Ani Pharmaceuticals IncANIPShares$11.3M147K
Capricor Therapeutics IncCAPRCall$10.6M350K
Contineum Therapeutics IncCTNMShares$10.6M808K
Ultragenyx Pharmaceutical InRAREShares$10.1M483K
Ionis Pharmaceuticals IncIONSShares$9.5M127K
Revolution Medicines IncRVMDPut$9.2M95K
Olema Pharmaceuticals IncOLMAShares$8.9M598K
Eupraxia Pharmaceuticals IncEPRXShares$8.8M1.2M
Damora Therapeutics IncDMRAShares$8.7M336K
Ionis Pharmaceuticals IncIONSCall$8.4M112K
Olema Pharmaceuticals IncOLMACall$8.2M550K
Palvella Therapeutics Inc NePVLAShares$8.1M65K
Fulcrum Therapeutics IncFULCShares$8.0M1.0M
Vera Therapeutics IncVERAShares$8.0M200K
Spruce Biosciences IncSPRBShares$7.9M121K
Inventiva SaIVAShares$7.8M1.4M
Jade Biosciences IncJBIOShares$7.2M512K
Ocugen IncOCGNShares$7.2M4.0M
Zura Bio LtdShares$7.1M1.2M
Ovid Therapeutics IncOVIDShares$6.4M2.9M
Abivax SaABVXShares$6.2M58K
Eli Lilly & CoLLYShares$6.0M7K
Avalo Therapeutics IncAVTXCall$6.0M402K
Alumis IncALMSCall$5.8M265K
Uniqure NvCall$5.8M355K
Alpha Cognition IncACOGShares$5.8M1.1M
Pelthos Therapeutics IncPTHSShares$5.4M257K
Karyopharm Therapeutics IncKPTICall$5.1M920K
Karyopharm Therapeutics IncKPTIPut$5.1M920K
Surrozen IncSRZNShares$5.0M173K
Tectonic Therapeutic IncTECXShares$4.9M158K
Eyepoint IncEYPTCall$4.8M370K
Eyepoint IncEYPTPut$4.8M370K
Alector IncALECShares$4.5M2.1M
Bridgebio Pharma IncBBIOCall$4.3M59K
Kymera Therapeutics IncKYMRPut$4.2M50K
Legend Biotech CorpLEGNShares$4.1M227K
Karyopharm Therapeutics IncKPTIShares$4.1M733K
Lipocine Inc NewLPCNShares$4.1M509K
Delcath Sys IncDCTHShares$4.0M431K
Kodiak Sciences IncKODCall$3.8M100K
Arvinas IncARVNShares$3.8M358K
Compass Pathways PlcCMPSShares$3.7M675K
Cardiol Therapeutics IncCRDLShares$3.7M2.7M
Celldex Therapeutics Inc NewCLDXPut$3.6M114K
Arrowhead Pharmaceuticals InARWRPut$3.6M58K
Biohaven LtdShares$3.5M412K
Invivyd IncIVVDShares$3.5M2.7M
Enliven Therapeutics IncELVNPut$3.3M84K
Annexon IncANNXShares$3.2M580K
Forte Biosciences IncFBRXShares$3.1M119K
Lexeo Therapeutics IncLXEOShares$2.9M513K
Vera Therapeutics IncVERACall$2.9M72K
Perceptive Cap Solutions CorShares$2.6M241K
Vir Biotechnology IncVIRShares$2.6M293K
Nextcure IncNXTCShares$2.5M238K
Neumora Therapeutics Inc.NMRAShares$2.5M1.3M
Acumen Pharmaceuticals IncABOSShares$2.5M1.1M
Cabaletta Bio IncCABAShares$2.4M900K
Bridgebio Oncology TherapeutBBOTShares$2.4M270K
Proqr Thrapeutics N VShares$2.4M1.5M
Nuvalent Inc5AXShares$2.4M24K
Avalo Therapeutics IncAVTXPut$2.4M159K
Jazz Pharmaceuticals PlcShares$2.4M12K
Replimune Group IncREPLPut$2.3M300K
Dbv Technologies S ADBVTShares$2.2M525K
Tarsus Pharmaceuticals IncTARSShares$2.2M31K
Kalaris Therapeutics IncKLRSShares$2.1M360K
Anteris Technologies GlobalAVRShares$2.0M367K
Solid Biosciences IncSLDBShares$1.9M264K

Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.