Exome Asset Management Llc
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$193.3M
Q ending 2026-03-31
Prior quarter
$209.1M
Q ending 2025-12-31
Change
-7.6% QoQ · +71.9% YoY
Positions
56
reported holdings
Largest positions
All 56 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Praxis Precision Medicines I | PRAX | Shares | $14.6M | 45K |
| Cogent Biosciences Inc | COGT | Shares | $10.7M | 279K |
| Enliven Therapeutics Inc | ELVN | Shares | $8.6M | 220K |
| Ionis Pharmaceuticals Inc | IONS | Shares | $8.3M | 110K |
| Spdr Series Trust | XBI | Put | $7.7M | 60K |
| Guardant Health Inc | GH | Shares | $7.6M | 83K |
| Cytokinetics Inc | CYTK | Shares | $6.8M | 104K |
| Eli Lilly & Co | LLY | Shares | $6.4M | 7K |
| Alumis Inc | ALMS | Shares | $6.2M | 279K |
| Bridgebio Pharma Inc | BBIO | Shares | $5.0M | 67K |
| Vera Therapeutics Inc | VERA | Shares | $4.6M | 115K |
| Insmed Inc | INSM | Shares | $4.4M | 27K |
| Elevance Health Inc Formerly | ELV | Shares | $4.3M | 15K |
| Agios Pharmaceuticals Inc | AGIO | Shares | $4.2M | 125K |
| United Therapeutics Corp Del | UTHR | Shares | $4.2M | 7K |
| Moonlake Immunotherapeutics | MLTX | Shares | $4.0M | 215K |
| Cytokinetics Inc | Put | $4.0M | 60K | |
| Natera Inc | NTRA | Shares | $3.7M | 19K |
| Rhythm Pharmaceuticals Inc | RYTM | Shares | $3.5M | 41K |
| Unitedhealth Group Inc | UNH | Shares | $3.5M | 13K |
| Apellis Pharmaceuticals Inc | APLS | Shares | $3.4M | 86K |
| Verastem Inc | VSTM | Shares | $3.4M | 637K |
| 10X Genomics Inc | TXG | Shares | $3.3M | 154K |
| Boston Scientific Corp | BSX | Shares | $3.0M | 48K |
| Alkermes Plc | Shares | $3.0M | 84K | |
| Beone Medicines Ltd | Call | $3.0M | 10K | |
| Monte Rosa Therapeutics Inc | GLUE | Shares | $3.0M | 179K |
| Intuitive Surgical Inc | ISRG | Shares | $2.9M | 6K |
| Adagene Inc | ADAG | Shares | $2.9M | 737K |
| Arrowhead Pharmaceuticals In | ARWR | Shares | $2.9M | 46K |
| Crescent Biopharma Inc. | Shares | $2.8M | 153K | |
| Relay Therapeutics Inc | RLAY | Shares | $2.8M | 278K |
| Maze Therapeutics Inc | MAZE | Shares | $2.6M | 89K |
| Cytomx Therapeutics Inc. | CTMX | Shares | $2.5M | 521K |
| Avalo Therapeutics Inc | AVTX | Shares | $2.4M | 159K |
| Alumis Inc | Put | $2.3M | 105K | |
| Glaukos Corp | GKOS | Shares | $2.2M | 21K |
| Corbus Pharmaceuticals Hldgs | CRBP | Shares | $2.2M | 234K |
| Penumbra Inc | PEN | Shares | $2.1M | 6K |
| Soleno Therapeutics Inc | SLNOEUR | Shares | $2.1M | 62K |
| Liquidia Corporation | LQDA | Shares | $1.7M | 46K |
| Zenas Biopharma Inc | ZBIO | Shares | $1.6M | 81K |
| Liquidia Corporation | Put | $1.5M | 40K | |
| Novabridge Biosciences | NBP | Shares | $1.4M | 577K |
| Centessa Pharmaceuticals Plc | Put | $1.4M | 35K | |
| Ideaya Biosciences Inc | Call | $1.3M | 40K | |
| Ideaya Biosciences Inc | Put | $1.3M | 40K | |
| 4D Molecular Therapeutics In | FDMT | Shares | $1.2M | 131K |
| Nextcure Inc | NXTC | Shares | $1.2M | 116K |
| Palisade Bio Inc | PALI | Shares | $1.1M | 600K |
| Establishment Labs Hldgs Inc | Shares | $744K | 13K | |
| Travere Therapeutics Inc | Put | $594K | 20K | |
| Lipocine Inc New | LPCN | Shares | $486K | 61K |
| Arbutus Biopharma Corp | ABUS | Shares | $340K | 75K |
| Wave Life Sciences Ltd | Put | $218K | 30K | |
| Compass Therapeutics Inc | Call | $133K | 25K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.