Dafna Capital Management Llc
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$439.6M
Q ending 2026-03-31
Prior quarter
$430.5M
Q ending 2025-12-31
Change
+2.1% QoQ · +24.6% YoY
Positions
83
reported holdings
Largest positions
All 83 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| Revolution Medicines Inc | RVMD | Shares | $56.5M | 581K |
| Spdr S&P Biotech Etf | XBI | Shares | $40.7M | 319K |
| Stereotaxis Inc | STXS | Shares | $25.2M | 13.7M |
| Day One Biopharmaceuticals I | DAWNGBX | Shares | $21.0M | 978K |
| Atricure Inc | ATRC | Shares | $17.0M | 597K |
| Ideaya Biosciences Inc | IDYA | Shares | $15.9M | 477K |
| Xenon Pharmaceuticals Inc | XENE | Shares | $14.6M | 251K |
| Cytokinetics Inc | CYTK | Shares | $14.3M | 217K |
| Compass Pathways Plc | CMPS | Shares | $13.4M | 2.4M |
| Nektar Therapeutics | NKTR | Shares | $11.9M | 165K |
| Ishares Nasdaq Biotech Indx | IBB | Shares | $10.5M | 62K |
| Arcus Biosciences Inc | RCUS | Shares | $9.6M | 444K |
| Neurocrine Biosciences Inc | NBIX | Shares | $9.3M | 71K |
| Larimar Therapeutics Inc | LRMR | Shares | $9.1M | 2.0M |
| Bicara Therapeutics Inc | BCAX | Shares | $8.4M | 422K |
| Axogen Inc | AXGN | Shares | $8.3M | 250K |
| Biohaven Ltd | Shares | $7.2M | 846K | |
| Tandem Diabetes Care Inc | TNDM | Shares | $6.8M | 355K |
| Denali Therapeutics Inc | DNLI | Shares | $6.1M | 319K |
| Ascendis Pharma A/S | ASND 2.25 04/01/28 | Principal | $5.9M | 4.0M |
| Century Therapeutics Inc | IPSC | Shares | $5.5M | 2.4M |
| Dexcom Inc | DXCM | Shares | $5.4M | 86K |
| Kalvista Pharmaceuticals Inc | 4XC1 | Shares | $5.4M | 267K |
| Ascendis Pharma A/S | Shares | $5.3M | 23K | |
| Mbx Biosciences Inc | MBX | Shares | $5.2M | 175K |
| Inogen Inc | INGN | Shares | $5.2M | 845K |
| Syndax Pharmaceuticals Inc | SNDX | Shares | $5.1M | 217K |
| Alkermes Plc | Shares | $4.9M | 139K | |
| Stoke Therapeutics Inc | STOK | Shares | $4.3M | 131K |
| Biocryst Pharmaceuticals Inc | BCRX | Shares | $4.1M | 430K |
| Galapagos Nv | LKFT | Shares | $3.9M | 130K |
| Immunovant Inc | IMVT | Shares | $3.7M | 151K |
| Edgewise Therapeutics Inc | EWTX | Shares | $3.5M | 112K |
| Maplight Therapeutics Inc | MPLT | Shares | $3.5M | 171K |
| Allogene Therapeutics Inc | ALLO | Shares | $3.3M | 1.4M |
| Procept Biorobotics Corp | PRCT | Shares | $3.0M | 120K |
| Align Technology Inc | ALGN | Shares | $2.6M | 15K |
| Proqr Therapeutics N V | Shares | $2.5M | 1.6M | |
| Cybin Inc | HELP | Shares | $2.4M | 498K |
| Rapport Therapeutics Inc | RAPP | Shares | $2.3M | 75K |
| Insulet Corp | PODD | Shares | $2.3M | 11K |
| Structure Therapeutics Inc | GPCR | Shares | $2.2M | 47K |
| Immatics Nv | Shares | $2.2M | 226K | |
| Celldex Therapeutics Inc | CLDX | Shares | $2.2M | 69K |
| Lexeo Therapeutics Inc | LXEO | Shares | $2.2M | 377K |
| Alector Inc | ALEC | Shares | $2.0M | 908K |
| Viking Therapeutics Inc | VKTX | Shares | $1.9M | 60K |
| Kura Oncology Inc | KURA | Shares | $1.9M | 236K |
| Profound Medical Corp | PROF | Shares | $1.7M | 263K |
| Fulcrum Therapeutics Inc | FULC | Shares | $1.6M | 205K |
| Aquestive Therapeutics Inc | AQST | Shares | $1.5M | 368K |
| Mediwound Ltd | Shares | $1.5M | 94K | |
| Orthopediatrics Corp | KIDS | Shares | $1.5M | 96K |
| Ultragenyx Pharmaceutical Inc | RARE | Shares | $1.3M | 61K |
| Engene Holdings Inc | Shares | $1.3M | 187K | |
| Neurogene Inc | NGNE | Shares | $1.1M | 57K |
| Ars Pharmaceuticals Inc | SPRY | Shares | $1.1M | 139K |
| Cytomx Therapeutics Inc | CTMX | Shares | $1.1M | 230K |
| Maze Therapeutics Inc | MAZE | Shares | $1.0M | 35K |
| Mineralys Therapeutics Inc | MLYS | Shares | $1.0M | 38K |
| Scynexis Inc | SCYXEUR | Shares | $997K | 1.1M |
| Oric Pharmaceuticals Inc | ORIC | Shares | $945K | 99K |
| Inspire Medical Systems Inc | INSP | Shares | $939K | 18K |
| Polypid Ltd | Shares | $911K | 208K | |
| Tela Bio Inc | TELA | Shares | $893K | 1.4M |
| Zenas Biopharma Inc | ZBIO | Shares | $831K | 43K |
| Verrica Pharmaceuticals Inc | VRCA | Shares | $813K | 154K |
| Fate Therapeutics Inc | FATE | Shares | $660K | 550K |
| Annexon Inc | ANNX | Shares | $653K | 118K |
| Accuray Inc | ARAY | Shares | $652K | 1.7M |
| Newamsterdam Pharma Co | Shares | $640K | 20K | |
| Adicet Bio Inc | ACET | Shares | $639K | 94K |
| Biontech Se | BNTX | Shares | $622K | 7K |
| Pliant Therapeutics Inc | PLRX | Shares | $614K | 487K |
| Compugen Ltd | Shares | $549K | 258K | |
| Orchestra Biomed Holdings Inc | OBIO | Shares | $539K | 127K |
| Foghorn Therapeutics Inc | FHTX | Shares | $535K | 112K |
| Ibio Inc | IBIO | Shares | $368K | 194K |
| Bicycle Therapeutics Plc | BCYC | Shares | $299K | 64K |
| Adc Therapeutics Sa | Shares | $270K | 72K | |
| Karyopharm Therapeutics Inc | KPTI | Shares | $255K | 46K |
| Autolus Therapeutics Ltd | AUTL | Shares | $247K | 179K |
| Neumora Therapeutics Inc | NMRA | Shares | $137K | 70K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.