Commodore Capital Lp

Institutional manager — quarterly 13F holdings, Q ending 2026-03-31

Reported value
$1.73B
Q ending 2026-03-31
Prior quarter
$1.50B
Q ending 2025-12-31
Change
+15.1% QoQ · +27.4% YoY
Positions
36
reported holdings

Largest positions

All 36 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
HoldingTickerTypeValueShares
Relay Therapeutics IncRLAYShares$169.2M17.0M
Alkermes PlcShares$148.5M4.2M
Enliven Therapeutics IncELVNShares$128.4M3.3M
Cogent Biosciences IncCOGTShares$111.2M2.9M
Spyre Therapeutics IncSYREShares$96.5M1.9M
Tyra Biosciences IncTYRAShares$94.8M2.5M
Celldex Therapeutics Inc NewCLDXShares$85.5M2.7M
Nuvalent Inc5AXShares$85.4M834K
Amylyx Pharmaceuticals IncAMLXShares$78.5M5.7M
Kymera Therapeutics IncKYMRShares$62.5M750K
Alto Neuroscience IncANROShares$61.2M2.7M
Pharvaris N VShares$54.2M1.9M
Erasca IncERASShares$51.4M3.2M
Damora Therapeutics IncDMRAShares$50.2M1.9M
Xenon Pharmaceuticals IncXENEShares$48.0M825K
Definium Therapeutics IncDFTXShares$37.8M2.0M
Lb Pharmaceuticals IncLBRXShares$37.0M1.5M
Eyepoint IncEYPTShares$36.4M2.8M
Nurix Therapeutics IncNRIXShares$35.3M2.3M
Corvus Pharmaceuticals IncCRVSShares$33.0M2.3M
Assembly Biosciences IncASMBShares$27.8M1.0M
Perspective Therapeutics IncCATXShares$26.4M6.3M
Soleno Therapeutics IncSLNOEURShares$21.8M652K
Ocular Therapeutix IncOCULShares$21.8M2.6M
Century Therapeutics IncIPSCShares$19.7M8.7M
Zura Bio LtdShares$19.3M3.3M
Sab Biotherapeutics IncSABSShares$16.9M4.4M
Palisade Bio IncPALIShares$12.6M7.2M
Karyopharm Therapeutics IncKPTIShares$10.9M1.9M
Inhibikase Therapeutics IncIKTShares$9.1M5.4M
An2 Therapeutics IncANTXShares$8.0M2.3M
Pepgen IncPEPGShares$7.9M4.5M
Avalo Therapeutics IncAVTXShares$7.2M483K
Helix Acquisition Corp IiiShares$5.1M500K
Leonabio IncLONAShares$4.8M464K
Relmada Therapeutics IncRLMDShares$4.4M634K

Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.