Avoro Capital Advisors Llc
Institutional manager — quarterly 13F holdings, Q ending 2026-03-31
Reported value
$10.16B
Q ending 2026-03-31
Prior quarter
$10.17B
Q ending 2025-12-31
Change
-0.1% QoQ · +58.7% YoY
Positions
32
reported holdings
Largest positions
All 32 reported positions, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
| Holding | Ticker | Type | Value ▼ | Shares |
|---|---|---|---|---|
| United Therapeutics Corp | UTHR | Shares | $1.56B | 2.6M |
| Ascendis Pharma | Shares | $1.16B | 5.1M | |
| Madrigal Pharmaceuticals Inc | MDGL | Shares | $951.8M | 1.8M |
| Krystal Biotech Inc | KRYS | Shares | $746.3M | 2.9M |
| Argenx Se | ARGX | Shares | $730.3M | 1.0M |
| Arrowhead Pharmaceuticals Inc | ARWR | Shares | $670.9M | 10.7M |
| Kymera Therapeutics Inc | KYMR | Shares | $622.6M | 7.5M |
| Apellis Pharmaceuticals Inc | APLS | Shares | $491.7M | 12.2M |
| Centessa Pharmaceuticals Plc | 260 | Shares | $454.0M | 11.4M |
| Celcuity Inc | CELC | Shares | $385.2M | 3.4M |
| Xenon Pharmaceuticals Inc | XENE | Shares | $336.0M | 5.8M |
| Structure Therapeutics Inc | GPCR | Shares | $316.0M | 6.6M |
| Terns Pharmaceuticals Inc | 430 | Shares | $300.2M | 5.7M |
| Vera Therapeutics Inc | VERA | Shares | $236.9M | 5.9M |
| Revolution Medicines Inc | RVMD | Shares | $228.0M | 2.3M |
| Cytokinetics Inc | CYTK | Shares | $219.7M | 3.3M |
| Ocular Therapeutix Inc | OCUL | Shares | $104.3M | 12.3M |
| Damora Therapeutics Inc | DMRA | Shares | $98.0M | 3.8M |
| Uniqure Nv | Shares | $97.4M | 6.0M | |
| Taysha Gene Therapies Inc | TSHA | Shares | $97.0M | 21.7M |
| Definium Therapeutics Inc | DFTX | Shares | $94.5M | 5.0M |
| Soleno Therapeutics Inc | SLNOEUR | Shares | $77.0M | 2.3M |
| Alkermes Plc | Shares | $42.4M | 1.2M | |
| Septerna Inc | SEPN | Shares | $32.1M | 1.3M |
| Viridian Therapeutics Inc | VRDN | Shares | $29.3M | 1.5M |
| Gh Research Plc | Shares | $25.3M | 1.8M | |
| Avalo Therapeutics | AVTX | Shares | $21.1M | 1.4M |
| Lexeo Therapeutics Inc | LXEO | Shares | $10.8M | 1.9M |
| United Therapeutics Corp | UTHR | Call | $10.3M | 380K |
| Whitehawk Therapeutics Inc | WHWK | Shares | $9.8M | 2.8M |
| Mannkind Corp | MNKD | Shares | $5.4M | 2.2M |
| Celcuity Inc | CELC | Call | $3.0M | 200K |
Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.