Affinity Asset Advisors, Llc

Institutional manager — quarterly 13F holdings, Q ending 2026-03-31

Reported value
$1.94B
Q ending 2026-03-31
Prior quarter
$1.76B
Q ending 2025-12-31
Change
+10.3% QoQ · +84.8% YoY
Positions
105
reported holdings

Largest positions

Top 100 of 105 reported positions by value, Q ending 2026-03-31. A manager can hold shares, calls and puts on the same security at once — such positions are listed as separate rows. Type: Shares = common stock, Put/Call = option positions (valued at the underlying), Principal = debt. Tickers link to stock pages where covered.
HoldingTickerTypeValueShares
State Str Spdr S&P 500 Etf TSPYPut$130.1M200K
Apogee Therapeutics IncAPGEShares$108.2M1.3M
Xenon Pharmaceuticals IncXENEShares$97.4M1.7M
Erasca IncERASShares$86.6M5.3M
Insmed IncINSMShares$78.5M480K
Roivant Sciences LtdShares$77.6M2.8M
Spyre Therapeutics IncSYREShares$64.5M1.3M
Centessa Pharmaceuticals Plc260Shares$55.6M1.4M
Praxis Precision Medicines IPRAXShares$54.8M170K
Anaptysbio IncANABShares$52.1M940K
Alkermes PlcShares$47.7M1.4M
Cytokinetics IncCYTKShares$46.2M700K
Abivax SaABVXShares$45.1M405K
Teva Pharmaceutical Inds LtdTEVAShares$42.2M1.4M
Arcellx IncACLXShares$41.7M363K
Moderna IncMRNACall$40.6M800K
Nuvalent Inc5AXShares$30.7M300K
Terns Pharmaceuticals Inc430Shares$29.7M563K
Dianthus Therapeutics IncDNTHShares$29.4M350K
Lexeo Therapeutics IncLXEOShares$29.0M5.1M
Cogent Biosciences IncCOGTShares$28.9M750K
Madrigal Pharmaceuticals IncMDGLShares$28.8M55K
Sutro Biopharma IncSTROShares$26.6M1.1M
Forte Biosciences IncFBRXShares$26.2M1.0M
Oruka Therapeutics IncORKAShares$24.5M500K
Trevi Therapeutics IncTRVIShares$23.9M2.0M
Ovid Therapeutics IncOVIDShares$23.6M10.6M
Enliven Therapeutics IncELVNShares$23.0M587K
Ascendis Pharma A/SShares$21.7M95K
Mineralys Therapeutics IncMLYSShares$20.3M750K
Avalo Therapeutics IncAVTXShares$20.0M1.3M
Bristol-Myers Squibb CoBMYCall$18.2M300K
Protagonist Therapeutics IncPTGXShares$18.1M172K
Celldex Therapeutics Inc NewCLDXShares$15.9M500K
Zura Bio LtdShares$15.3M2.6M
Nurix Therapeutics IncNRIXShares$15.0M968K
Savara IncSVRAShares$13.7M2.5M
Omeros CorpOMER 9.5 06/15/29Principal$13.2M6.5M
Perspective Therapeutics IncCATXShares$13.2M3.2M
Helix Acquisition Corp IiiShares$12.7M1.3M
Arrowhead Pharmaceuticals InARWRShares$12.5M200K
Damora Therapeutics IncDMRAShares$11.7M450K
Eupraxia Pharmaceuticals IncEPRXShares$11.5M1.6M
Alto Neuroscience IncANROShares$11.2M500K
Bridgebio Pharma IncBBIOShares$11.1M150K
Cullinan Therapeutics IncCGEMShares$11.1M781K
Belite Bio IncBLTEShares$10.4M65K
Wave Life Sciences LtdShares$10.2M1.4M
Vera Therapeutics IncVERAShares$10.1M250K
Tyra Biosciences IncTYRAShares$9.9M258K
Revolution Medicines IncRVMDShares$9.7M100K
Revolution Medicines IncRVMDPut$9.7M100K
Immunitybio IncIBRXPut$9.6M1.3M
Jade Biosciences IncJBIOShares$9.0M640K
Travere Therapeutics IncTVTXShares$8.9M300K
Newamsterdam Pharma CompanyShares$8.8M275K
Cogent Biosciences IncCOGT 1.625 11/15/31Principal$8.6M7.0M
Korro Bio IncKRROShares$8.0M707K
Celcuity IncCELC 2.75 08/01/31Principal$7.3M3.0M
Crispr Therapeutics AgShares$7.1M150K
Spyglass Pharma IncSGPShares$6.5M250K
Novo-Nordisk A SNVOCall$6.4M175K
Compass Pathways PlcCMPSShares$6.1M1.1M
Ibio IncIBIOShares$5.9M3.1M
Establishment Labs Hldgs IncShares$5.7M100K
Anteris Technologies GlobalAVRShares$5.1M912K
Newamsterdam Pharma CompanyShares$4.9M245K
Uniqure NvCall$4.9M300K
Viridian Therapeutics IncVRDNShares$4.9M250K
Climb Bio IncCLYMShares$4.8M700K
Rezolute IncRZLTShares$4.7M1.5M
Sagimet Biosciences IncSGMTShares$4.5M868K
Mbx Biosciences IncMBXShares$4.5M150K
Taysha Gene Therapies IncTSHAShares$4.5M1.0M
Veradermics IncMANEShares$4.4M70K
Generate Biomedicines IncGENBShares$4.4M350K
Dianthus Therapeutics IncDNTHCall$4.2M50K
Engene Holdings IncShares$4.2M610K
Cg Oncology IncCGONCall$4.1M60K
Arrivent Biopharma IncAVBPShares$4.0M175K
Relay Therapeutics IncRLAYShares$4.0M400K
Proqr Thrapeutics N VShares$4.0M2.5M
Verrica Pharmaceuticals IncVRCAShares$3.7M707K
Celcuity IncCELCCall$3.4M30K
Precision Biosciences IncDTILShares$3.3M598K
Karyopharm Therapeutics IncKPTIShares$2.8M500K
Sol-Gel Technologies LtdShares$2.8M35K
Crinetics Pharmaceuticals InCRNXShares$2.7M75K
Oaktree Acquisition Corp IiiShares$2.7M250K
Nextcure IncNXTCShares$2.6M242K
Immunovant IncIMVTShares$2.5M100K
Equillium IncEQShares$2.5M1.2M
Sab Biotherapeutics IncSABSShares$2.2M575K
Corcept Therapeutics IncCORTShares$2.0M50K
Orchestra Biomed Hldgs IncOBIOShares$1.7M403K
Kezar Life Sciences Inc2KZ0Shares$1.7M229K
Macrogenics IncMGNXShares$1.4M500K
Adlai Nortye LtdANLShares$1.1M165K
Alector IncALECShares$1.1M500K
Onkure Therapeutics IncOKURShares$998K241K

Values as reported in public regulatory filings (USD); holdings are reported quarterly, up to 45 days after quarter end, and may contain reporting errors. Nothing here is investment advice.